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Robert W Colman Selected Research

High-Molecular-Weight Kininogen (Kininogen, High Molecular Weight)

1/2019Correction: An essential role of high-molecular-weight kininogen in endotoxemia.
1/2017An essential role of high-molecular-weight kininogen in endotoxemia.
12/2010Inhibition of metastasis of syngeneic murine melanoma in vivo and vasculogenesis in vitro by monoclonal antibody C11C1 targeted to domain 5 of high molecular weight kininogen.
2/2010Upregulation of tissue factor in monocytes by cleaved high molecular weight kininogen is dependent on TNF-alpha and IL-1beta.
9/2007Kininostatin associates with membrane rafts and inhibits alpha(v)beta3 integrin activation in human umbilical vein endothelial cells.
1/2006Regulation of angiogenesis by the kallikrein-kinin system.
11/2005[High molecular weight kininogen in inflammation and angiogenesis: a review of its properties and therapeutic applications].
8/2005Modulation of inflammation by kininogen deficiency in a rat model of inflammatory arthritis.
1/2005The role of plasma high molecular weight kininogen in experimental intestinal and systemic inflammation.
10/2004Inhibition of tumor angiogenesis in vivo by a monoclonal antibody targeted to domain 5 of high molecular weight kininogen.
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Robert W Colman Research Topics

Disease

15Inflammation (Inflammations)
01/2018 - 07/2002
9Arthritis (Polyarthritis)
12/2017 - 09/2004
6Neoplasms (Cancer)
11/2010 - 12/2002
6Crohn Disease (Crohn's Disease)
01/2006 - 08/2002
6Enterocolitis
11/2005 - 07/2002
4Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
02/2010 - 03/2003
4Thrombosis (Thrombus)
06/2007 - 07/2004
4Rheumatoid Arthritis
01/2006 - 09/2004
3Hemorrhage
03/2006 - 01/2005
2Endotoxemia
01/2019 - 01/2017
2Multiple Myeloma
12/2010 - 07/2006
2Sepsis (Septicemia)
02/2010 - 01/2006
2Wounds and Injuries (Trauma)
03/2006 - 08/2005
2Ulcerative Colitis
08/2005 - 03/2003
2Granuloma
08/2005 - 03/2003
2Carcinoma (Carcinomatosis)
10/2004 - 12/2002
1Colitis
01/2018
1Body Weight (Weight, Body)
01/2018
1Experimental Arthritis
11/2012
1Colonic Neoplasms (Colon Cancer)
12/2010
1Neoplasm Metastasis (Metastasis)
12/2010
1Melanoma (Melanoma, Malignant)
12/2010
1Hypotension (Low Blood Pressure)
03/2007
1Systemic Inflammatory Response Syndrome (Sepsis Syndrome)
11/2005
1Surgical Wound
08/2005
1Pain (Aches)
08/2005
1Psoriasis (Pustulosis Palmaris et Plantaris)
01/2005
1Retinoblastoma (Glioblastoma, Retinal)
09/2004
1Reactive Arthritis (Reiter Disease)
09/2004
1Genetic Predisposition to Disease (Genetic Predisposition)
10/2003
1Infections
06/2003
1Vascular System Injuries
06/2003
1Diverticulitis
08/2002

Drug/Important Bio-Agent (IBA)

16High-Molecular-Weight Kininogen (Kininogen, High Molecular Weight)IBA
01/2019 - 07/2002
9Plasma KallikreinIBA
01/2018 - 09/2004
8Kininogens (Kininogen)IBA
01/2018 - 07/2002
7KininsIBA
11/2012 - 08/2002
7Monoclonal AntibodiesIBA
12/2010 - 12/2002
7Polysaccharides (Glycans)IBA
08/2005 - 07/2002
7Peptidoglycan (Murein)IBA
08/2005 - 07/2002
6Proteins (Proteins, Gene)FDA Link
01/2018 - 03/2003
4BradykininIBA
01/2018 - 08/2005
4PolymersIBA
01/2005 - 07/2002
3Bradykinin Receptors (Bradykinin Receptor)IBA
01/2018 - 08/2005
3CytokinesIBA
01/2018 - 02/2010
3Peptides (Polypeptides)IBA
06/2007 - 12/2002
3Blood Proteins (Serum Proteins)IBA
01/2006 - 10/2004
2FibrinIBA
06/2007 - 08/2005
2ThrombinFDA Link
06/2007 - 08/2005
2Thomsen-Friedenreich antigenIBA
03/2006 - 08/2005
2Tissue Kallikreins (Tissue Kallikrein)IBA
03/2003 - 08/2002
1Sulfonic AcidsIBA
01/2018
1Dextran SulfateIBA
01/2018
1sym-trinitrobenzeneIBA
01/2018
1AutoantibodiesIBA
12/2017
1Kallikreins (Kallikrein)IBA
11/2012
1S100 Proteins (S 100 Protein)IBA
12/2010
1Neoplasm Antigens (Tumor Antigens)IBA
12/2010
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
11/2010
1Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
11/2010
1AntibodiesIBA
02/2010
1PeptidomimeticsIBA
02/2010
1src-Family KinasesIBA
02/2008
1clotting enzymeIBA
03/2006
1Pharmaceutical PreparationsIBA
03/2006
1Factor XII (Hageman Factor)IBA
03/2006
1benzoyl-prolyl-phenylalanyl-boroarginineIBA
11/2005
1Factor VII (Proconvertin)IBA
08/2005
1Heparin (Liquaemin)FDA LinkGeneric
08/2005
1Factor X (Stuart Factor)IBA
08/2005
1Factor VIIa (Activated Factor VII)IBA
08/2005
1Thromboplastin (Tissue Factor)IBA
08/2005
1Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
08/2005
1Biomarkers (Surrogate Marker)IBA
01/2005
1HLA Antigens (Human Leukocyte Antigens)IBA
01/2005
1HLA-B27 Antigen (HLA B27 Antigen)IBA
01/2005
1Immunoglobulin G (IgG)IBA
10/2004
1Cyclin-Dependent Kinases (cdk Proteins)IBA
09/2004
1Retinoblastoma ProteinIBA
09/2004
1Adenosine Monophosphate (AMP)IBA
08/2004
1Phosphoric Diester Hydrolases (Phosphodiesterases)IBA
08/2004
1LigandsIBA
07/2004
1Complement System Proteins (Complement)IBA
07/2004
1IntegrinsIBA
06/2003
1adhesion receptorIBA
06/2003
1Peptide Hydrolases (Proteases)FDA Link
06/2003
1kallistatinIBA
03/2003
1PrekallikreinIBA
08/2002
1Factor XI (Plasma Thromboplastin Antecedent)IBA
08/2002
1AntigensIBA
08/2002

Therapy/Procedure

5Therapeutics
02/2010 - 12/2002
3Cardiopulmonary Bypass (Heart-Lung Bypass)
03/2006 - 01/2005
3Intraperitoneal Injections
08/2005 - 09/2004
2Drug Therapy (Chemotherapy)
01/2005 - 09/2004
1Intravenous Injections
01/2018